Description
Product Characteristics:
Aliases: Alkaline phosphodiesterase 1 antibody, ARHR2 antibody, COLED antibody, E-NPP 1 antibody, Ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 antibody, ENPP1 antibody, ENPP1_HUMAN antibody, Ly 41 antigen antibody, M6S1 antibody, Membrane component chromosome 6 surface marker 1 antibody, NPP1 antibody, NPPase antibody, NPPS antibody, Nucleotide pyrophosphatase antibody, PC 1 antibody, PC-1 antibody, PCA1 antibody, PDNP1 antibody, Phosphodiesterase I/nucleotide pyrophosphatase 1 antibody, Plasma cell membrane glycoprotein 1 antibody, Plasma-cell membrane glycoprotein PC-1 antibody
Target Information: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008]